{"id":69,"date":"2011-12-08T19:06:04","date_gmt":"2011-12-08T19:06:04","guid":{"rendered":"https:\/\/wordpress.clarku.edu\/nmeyer\/?page_id=69"},"modified":"2012-08-20T13:50:50","modified_gmt":"2012-08-20T13:50:50","slug":"fate-mapping","status":"publish","type":"page","link":"https:\/\/wordpress.clarku.edu\/nmeyer\/research\/fate-mapping\/","title":{"rendered":"Fate Mapping"},"content":{"rendered":"<p>As a complement to\u00a0molecular studies in <em>C. teleta<\/em>, my lab is also interested in using fate mapping to learn more about development of <em>C. teleta<\/em> and spiralians in general.\u00a0 <em>C. teleta<\/em> develops by spiral cleavage, a highly stereotypical cleavage program that is found throughout the spiralians.\u00a0 This stereotypy allows homologous blastomeres<br \/>\nto be recognized across taxa even though their body plans appear diverse, thus<br \/>\nfacilitating reconstruction of the evolution of structures.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-104\" style=\"margin: 0px 0px 10px 10px;border: 1px solid #827772\" src=\"https:\/\/wordpress.clarku.edu\/wp-content\/uploads\/sites\/59\/2011\/11\/2d04_Mnew1-300x199.jpg\" alt=\"\" width=\"300\" height=\"199\" srcset=\"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-content\/uploads\/sites\/59\/2011\/11\/2d04_Mnew1-300x199.jpg 300w, https:\/\/wordpress.clarku.edu\/nmeyer\/wp-content\/uploads\/sites\/59\/2011\/11\/2d04_Mnew1.jpg 480w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/>Previously, in my former post-doc lab, we\u00a0mapped early blastomere fate (through 32 cells) in <em>C. teleta<\/em> by <a href=\"https:\/\/wordpress.clarku.edu\/wp-content\/uploads\/sites\/59\/2011\/11\/MeyerSeaver-2010.pdf\" target=\"_blank\">intracellular lineage analysis<\/a>.\u00a0\u00a0 This fate map has allowed identification of\u00a0the blastomeres that\u00a0generate most of the structures in the animal, including the brain and ventral nerve cord.\u00a0 This also\u00a0allows for\u00a0injection of\u00a0reagents into a subset of tissues (e.g. the left side\u00a0versus the right side of the\u00a0brain).\u00a0 Furthermore, these cells can be followed in real time as the brain or ventral nerve cord develops and undergoes metamorphosis.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As a complement to\u00a0molecular studies in C. teleta, my lab is also interested in using fate mapping to learn more about development of C. teleta and spiralians in general.\u00a0 C. teleta develops by spiral cleavage, a highly stereotypical cleavage program that is found throughout the spiralians.\u00a0 This stereotypy allows homologous &#8230; <a class=\"continue-reading-link\" href=\"https:\/\/wordpress.clarku.edu\/nmeyer\/research\/fate-mapping\/\"> Continue reading<\/a><\/p>\n","protected":false},"author":93,"featured_media":254,"parent":7,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-69","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/pages\/69","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/users\/93"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/comments?post=69"}],"version-history":[{"count":0,"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/pages\/69\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/pages\/7"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/media\/254"}],"wp:attachment":[{"href":"https:\/\/wordpress.clarku.edu\/nmeyer\/wp-json\/wp\/v2\/media?parent=69"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}